The loss of FHIT expression did not correlate with histological type, cell differentiation, clinical stage and metastasis, but was frequently observed in tobacco smokers.
FHIT基因失活与吸烟相关，但与组织学类型、分化程度、临床分期和转移无关。
Methods: Matched normal and cancerous tissues from 41 patients with colorectal cancer and 25 patients with colorectal adenoma were examined for FHIT expression using RT-PCR.
方法：采用逆转录巢式酶链免疫反应，对41例结直肠癌组织及其配对的癌旁正常组织和25例良性腺瘤的FHIT基因进行检测。
Conclusion FHIT gene may play a role in the regulation of cell proliferation of lung cancer, and the reduction in FHIT expression may be related to the pathogenesis of lung cancer.
结论FHIT基因可能参与肿瘤细胞增殖的调控，FHIT基因表达下降可能与肺癌的发生密切相关。
应用推荐