VEGF121 is involved in angiogenesis, vascular endothelial cell survival, growth, migration and vascular permeability (1).

VEGF121参与到了血管再生、血管内皮细胞生存、生长、迁移和血管渗透(1)。

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Then cell morphological changes are induced, such as polarity, protrusion, and adhesion, which lead to the migration of endothelial cell at last.

这些级联反应引起细胞形态学上的进一步变化，如极化、突起、黏附，最终导致细胞的迁移运动。

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Objective: the aim of the present research is to study the selectivity of Mitomycin on human umbilical vein endothelial cells (HUVEC) function and cell migration and the mechanism was also discussed.

目的：观察丝裂霉素对人脐静脉血管内皮细胞(HUVEC)作用的选择性和细胞迁移能力的影响及机制研究。

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