Searching for the effect biomarkers of long-term and low-level exposure to op has a very important meaning in detection of the earlier harmful effect of exposed populations in time.

探讨长期低剂量接触OP的效应标志物，对于及时发现职业接触人群早期健康损害，预防和控制慢性农药中毒具有十分重要的意义。

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Abstract: the salivary peptidomics provides a new method for study of disease biomarkers, but the effect of frozen storage conditions on analysis results is not very clear.

摘要：唾液多肽组学为疾病相关的生物标记物研究提供了新方法，但冻存条件对分析结果的影响并不清楚。

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Molecular biomarkers can be used in early detection of biological effect, susceptible population, risk assessment and research on mechanism, treatment and prevention in diseases.

分子生物标志物的应用有助于我们早期识别生物学效应和易感人群，从而有利于毒物危险度评估，同时可用于发病机理和防治效果研究。

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