Drug metabolism enzymes (DME) play a significant role in drug detoxification and activation, which exert important effect on drug efficacy and sensitivity to toxicity.
药物代谢酶(DME)在药物代谢解毒和药物代谢活化中起着重要的作用，对组织器官的药物效应和毒性的易感性产生重要影响。
This review provides a better understanding of the cytochrome P450 system with a focus on those enzymes most involved in drug metabolism.
这次综述提供了一个对大多数药物代谢有关的酶为重点的细胞色素P 450系统的了解。
Predicting of drug metabolism in humans based on animal experiments is complicated by species differences in the catalytic properties of these enzymes.
根据动物实验来预测人体的药物代谢时，代谢酶的种属差异性会使这项研究工作变得非常困难。
应用推荐