Methods The effects of zinc supplementation were assessed in a double-blinded randomized control design.

方法随机双盲对照法补锌干预研究。

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Trials were included if they were randomized, double-blinded, and controlled with placebo or active comparator.

这些试验包括，是否是随机，双盲，安慰剂对照或活动比较仪。

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A total of 19 trials (16,390 patients) were included and these were all randomized, double-blinded and controlled with a placebo or with an active comparator.

总共有19个研究包含在内（有16390人参与），所有的研究都是随机的、双盲的、有安慰剂对照或者其他有效的对照。

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If both patients and health care providers are blinded, the trial is said to have a double-blinded design.

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Dr. Hartwell, who wasn't involved in the study, said social-network trials aren't likely to replace conventional randomized, double-blinded, placebo-controlled trials, the gold-standard for generating medical evidence.

WSJ: ALS Study Falls Short, But Use of Social Media Holds Promise