Objective to study an effective method in inducing donor specific tolerance as well as the effects on hematopoietic reconstitution after xenogeneic-bone marrow transplantation.
目的研究有效诱导异种骨髓移植耐受的方法和对异基因骨髓移植重建的影响。
Conclusions Intrathymic or intraperitoneal inoculation of allogeneic cells in a neonatal recipient with an immature system can produce donor specific tolerance to a subsequent graft.
结论单一胸腺或腹腔内注射同种脾细胞可以诱导新生大鼠的特异性免疫耐受。
Conclusion: Donor bone marrow transfusion was safe and beneficial. It could induce specific immunologic tolerance in the renal allograft recipients.
结论：同供体肾移植及骨髓细胞输注是一种可行的诱导免疫耐受的方法，且简便安全。
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