The dimerization domain of NEMO was mapped to residues 251-419 by deletion and yeast two-hybrid analyses.
我们首先应用缺失突变和酵母双杂交试验将NEMO的二聚化域确定于251-419残基。
It had long been known that the EGFR ligand dimerizes the receptor and that this dimerization converts into an activation of the kinase domain;
人们很早就知道，EGFR配体使受体二聚化，这种二聚化导致激酶结构域的激活；
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