Methods The healthy volunteers were divided into 6 different dose groups randomly for the clinical trial including 4 single dose groups and 2 multiple dose groups.
方法采用随机分组的观察方法，共分6个剂量组，即单次和累积给药剂量组，其中单次给药剂量组4个，累积给药剂量组2个。
The length and rate of DNA migration in low dose group were markedly different from medium and high dose groups. There was no significant difference between medium and high dose groups.
微核率随着甲醛剂量的增加而升高，迁移率和迁移度在低剂量组与中、高剂量组之间有显著差异，中与高剂量组之间无显著差异。
The dose of midazolam used, the sedative effect as well as the complications occurred at different time points in the two groups were observed and compared.
观察两组患者治疗前后不同时间咪唑安定用量、镇静效果、并发症的差别。
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