BACKGROUND: Muscarine receptor plays a key role in adjusting contraction of detrusor muscle cell, and M3R, isoforms of its receptor, can mediate contraction of detrusor muscle cell directly.
背景：毒蕈碱受体在调节逼尿肌细胞收缩过程中起重要作用，其受体亚型M3R直接介导逼尿肌细胞收缩。
Objective to investigate the relationship between phenotype transformation and biomechanical properties of detrusor smooth muscle cell (DSMC) subjected to the cyclic mechanical stretch.
目的探讨周期性张力作用下的逼尿肌细胞表型转化与其生物力学特性改变的关系。
Methods:Bladder detrusor urinae of rat were suspended in smooth muscle chambers and contractile activity were observed.
方法：将肌条置于离体平滑肌灌流肌槽内，用生理记录仪记录肌条的收缩活动。
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