Aim To evaluate colon delivery effects of dextran-prednisolone,a prodrug of prednisolone,in rats.
目的探讨以葡聚糖为载体的泼尼松龙前体药物在大鼠体内是否具结肠定位性。
参考来源 - 泼尼松龙前体药物的结肠定位研究 The Investigation of a Prednisolone Prodrug for ColonThe activated dextran or PVA molecule was immobilized on a surfacecontaining amino groups leaving a sufficient number of active groups for secondarybinding of biomolecules.
活化的葡聚糖和聚乙烯醇分子与表面带有氨基的固相偶联,得到的Hydrocoating活化固相制品可直接用来固定生物分子。
参考来源 - Hydrocoating 固相化学偶联技术的研究Long gold nanoparticles chain with good dispersion has been prepared based on the chemical oxidative between HAuCI4 and sodium citrate via using the biocompatible,water-soluble dextran as the template.
基于柠檬酸钠与氯金酸的氧化还原反应,通过用具有生物相容性、水溶性好的右旋糖苷作为模板,合成的金纳米颗粒发生自组装形成较长、分散性较好的金纳米链。
参考来源 - 金属—有机复合物的合成、组装及其在生化分析中的应用研究Therefore, dextran has a better modification effect on zinger protease than mPEG. Dextran is more suitable for the chemical modification of proteases and the development and utilization of novel enzymes.
结果表明:右旋糖苷对生姜蛋白酶的修饰效果优于聚乙二醇,适用于酶蛋白的化学修饰与新型酶制剂的开发利用。
参考来源 - 生姜蛋白酶的大分子结合修饰·2,447,543篇论文数据,部分数据来源于NoteExpress
N a polysaccharide produced by the action of bacteria on sucrose: used as a substitute for plasma in blood transfusions 葡萄聚糖 [biochem]
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