AIM: To investigate the distribution of genotype of CYP3AP1 in Chinese Han population and the correlation with CYP3A activity.
目的：研究中国汉族人群中CYP3AP1基因型的分布特征及其与CYP3A活性的相关性。
The activity of CYP3A was reflected by the pharmacokinetics of midazolam.
CYP3A酶活性通过咪达唑伦药代动力学参数进行反应。
Conclusion: High dose of daidzein tablets may inhibit the activity of CYP3A in vivo, which needs the awareness of physicians because of the potential drug interaction.
结论：大剂量服用黄豆苷元会对CYP3A酶产生轻度抑止作用，临床上的药物合用需要考虑到这个因素。
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