Among HCV encoding gene, core region shows greater sequence conservation. Core gene expression has favorable antigen stability.
在HCV的编码基因中，核心区(C区)序列具有高度遗传保守性，c基因表达产物具有良好的抗原稳定性。
Histone is the core of chromatin, and covalent modification of histone tails have fundamental roles in regulation of gene expression.
组蛋白是染色质的核心，其尾部共价修饰在基因表达调控中有重要作用。
Objective to explore the possibility of using HBV as a gene delivery vector, and to test the anti-HBV effects by intracellular expression of dominant negative mutants of core protein.
目的探索H BV作为基因治疗载体的可能性及检验HBV点突变表达显性阴性突变体抗hbv的作用。
应用推荐