AIM: To establish a model of human M5 leukemia and investigate the pathomorphological change in severe combined immunodeficient (SCID) mice after being transplanted with SHI-1 cells.

前言： 目的：建立人M5型白血病细胞系SHI-1/S CID（重症联合免疫缺陷）小鼠模型，探讨白血病细胞的接种密度与SCID小鼠成瘤率及病理变化的关系。

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In an in vivo model using severe combined immunodeficient mice, subcutaneous tumors were generated by inoculating the animals with cells from human non-small cell lung carcinoma cell lines.

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