The clinical literature on antidepressant drugs is massive, since large-scale, rigorous studies are required for market approval from the Food and Drug Administration (FDA).

自从食品与药物管理局（FDA）的支持以及市场对进行大规模的严格的研究的需要，关于抗抑郁药物方面的临床文献相当多。

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To provide some scientific basis for rational use of the funds, reduce overstocking of drugs, satisfy clinical actual needs and increase the level of drug administration.

为合理使用购药资金，减少药品积压，合理用药，满足临床实际需求及提高药品管理水平提供科学依据。

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OBJECTIVE:To investigate the utilization status and the developmental tendency of genetic engineering drugs for references of clinical rational administration.

目的：了解基因工程药物的临床使用现状和发展趋势，为临床合理使用提供参考。

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Dr Richard Kalpit, the clinical reviewer at the US Food and Drug Administration, the US drugs regulator, who approved the drug, told the BMJ he was not given the data included in the documents.

BBC: NEWS | Health | Journal hands over Prozac papers

In addition, and more specific to the sector, any bull market for the sector will come to an end if or when high profile drugs start to fail Phase III clinical trials or the Food and Drug Administration turns down a high profile drug that everyone was certain would be approved.

FORBES: Nate Pile's Small Cap Classroom