Conclusion Under chronic pressure overload, the activated ASK1 with the increasing ROS may play an important role in signal transduction pathway of myocardial hypertrophy.

结论压力超负荷下随着ROS的升高，激活的ASK1可能在心脏肥大信号传导途径中发挥重要作用。

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Objective: To study on the plasma level of at rial natriuretic polypeptide (ANP) and effect of digoxin in the rats with chronic congestive heart failure (CHF) by pressure overload.

目的：观察后负荷增加所致充血性心力衰竭(CHF)大鼠血浆心钠素(ANP)水平的变化及地高辛的影响。

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