The effect, of chronic intermittent hypobaric hypoxia on pulmonary vascular reactivity to acute hypoxia in. rats and its relationship to histamine have been studied.

作者研究了慢性间断低压缺氧对大鼠肺血管反应性的影响及其与组胺的关系。动物经慢性缺氧后发生慢性肺动脉高压，其肺血管对急性缺氧的反应性降低。

youdao

Chronic hypobaric hypoxia (lack of oxygen): where the expedition will encounter equivalent altitudes up around 3, 800m due to the extreme cold temperatures and distance from the Equator which further decreases atmospheric pressure.

BBC: Viewpoint: The last great polar challenge