To make a treatment effective, it must be tailored individually to each patient, and can change over time as the patient’s condition changes.

为了实现有效的治疗，必须针对每个病患进行量身定制，并且会随着病人病情的变化而随时间改变。

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Usually when people are sad, they don't du anything. They just cry over their condition. But when they get angry, they bring about change.

通常当人们难过时无法做任何事情，他们只会为现状而哭泣。但是当他们愤怒时，他们会改变现状。

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Based on its forming history and development condition, this article analyzed the cause of function change and over-breeding in eastern Taihu Lake.

根据东太湖形成的历史和演变情况，分析了该湖泊功能的变化。

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Dr. Nicholas Schiff, of the Weill Cornell Medical Center, in New York, told CNN that the risk of misdiagnosis is increased because a patient's condition can change over a long period and the transition from VS to MS often takes place outside the time window of careful assessment.

CNN: Trapped 'coma' man: How was he misdiagnosed?