Conclusions:The high S/D values can be caused by fetal anomalies, especially multi-malformations, gastrointestinal tract and central nervous system malformations.

结论：胎儿畸形，尤其是多发畸形、消化系统畸形和中枢神经系统畸形可引起S/ D值增高。

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Inhalation of toluene can cause pregnant women infants with malformations, fetal central nervous system dysfunction and growth retardation and other defects.

孕妇吸入大量甲苯可以会造成胎婴儿畸形、中枢神经系统功能障碍及生长发育迟缓等缺陷。

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Dr Lloyd-Evans explains that the absence of cholesterol in the brains of SLOS sufferers means that the neurons and the central nervous system are affected, causing anything from mild personality disorders to severe malformations and multi-organ disease.

BBC: 'No-one had heard of my boys' syndrome'