These alterations defined a core set of 12 cellular signaling pathways and processes that were each genetically altered in 67% to 100% of the tumors.
这些改变被定义为一组12个核心的细胞信号通路和过程,每个通路在肿瘤有67%到100%的改变。
The pathogenesis of pituitary adenomas is considered to be related with gene mutation, growth factors, cell receptors, transcription factors, and cellular signaling pathways.
目前认为垂体腺瘤的发生与基因突变、生长因子、细胞受体、转录因子和细胞信号通路等有关。
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