The replication of parvovirus is strongly dependent on cellular factors associated with proliferation and differentiation, especially those related to the S-phase of the cell cycle.
细小病毒的复制紧紧依赖于和增殖及分化有关的细胞因子，尤其是和细胞周期S-期有关的因子。
BACKGROUND: the different level of proteins regulating cell cycle and their correlation is the main criteria to differentiate the benign and malignant cellular proliferation.
背景：细胞周期调控蛋白水平及其相互关系是良恶性细胞增殖的主要区别标准。
This research reveals that SPATA4 gene can inhibit cellular senescence and apoptosis as well as promote the progression of cell cycle and cell proliferation;
本研究发现SPATA4基因能够抑制细胞衰老和细胞凋亡、促进细胞周期的推进与细胞增殖；
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