The de-normalization causes difficulty on data retrieval, analysis, and quality control.

这种不规范将为数据检索、分析和质量控制增加难度。

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People with autism often have difficulty in attributing mental states to others and this is thought to be one of the main causes of their struggle to know how other people feel.

孤独症患者常常无法猜测别人的心思，一般认为这就是他们无法了解别人感受的原因。

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URIs are limited to the ASCII subset of characters -- only 127 characters based on the needs of English-speaking users -- and this causes much difficulty for non-English users.

URI 被限定为只能使用 ASCII 字符子集 —— 只包含基于英语用户需求的 127 个字符 —— 这为非英语用户造成了很多障碍。

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That good-government precondition is crucial, however, and causes the team some difficulty.

ECONOMIST: Development

The steady loss of wage competitiveness relative to Germany has been one of the troubling and underlying causes of economic difficulty for a number of euro-zone members since the launch of the single currency.

WSJ: Odds Stacked Against Latest EU Pact

More severe heart failure causes swollen legs and the patient has difficulty breathing when lying flat.

CNN: Could childhood chemo cause heart problems for an adult?