Objective To explore whether diagnostic progression effects cancer specific mortality, incidence and 5 year survival rates.

目的探讨诊断技术进步对肿瘤发病率、死亡率和5年生存率带来的影响。

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Main outcome measures All cause mortality and cause specific mortality with the main focus on cancer and cardiovascular disease.

主要的评价结果指标：全死因死亡率以及恶性肿瘤、心血管疾病死亡专率。

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To determine whether screening for prostate cancer reduces prostate cancer-specific mortality or all-cause mortality and to assess its impact on quality of life and adverse events.

判断摄护腺癌筛检是否能降低摄护腺癌死亡率或总死亡率，并评估它对于生活品质及不良事件的影响。

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