本研究分离得到了Sca-1~+Lin~-小鼠骨髓间充质干细胞(bone marrow-MSCs,BM-MSCs),其在体外能够促进CD4~+幼稚T细胞分化为调节性T细胞,而抑制其分化为Th17细胞。
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Bone marrow MSCs also may contribute themselves to the constitution and function of hematopoietic microenvironment.
骨髓MSC本身也参与了造血微环境的组成及功能。
参考来源 - AcSDKP对体外培养条件下小鼠骨髓间充质干细胞生长的影响·2,447,543篇论文数据,部分数据来源于NoteExpress
One purpose of this study is to elucidate whether few engrafted MSCs could change the microenvironment of bone marrow to facilitate bone recovery.
本研究主要目的在探讨滞留在骨髓之移植干细胞,其改善骨质的效果是否有部分是藉由改变骨髓内的微环境所造成。
Because both fat tissue and bone marrow are tissues originated from mesoderm, so whether MSCs could be obtained from fat tissue as well, which also have multi - lineage differentiation potential?
由于脂肪组织与骨髓同为中胚层起源的组织,那么能否从脂肪组织中获得间充质干细胞,而且也具有多分化潜能呢?
Conclusion: The evident difference is not found in biological characteristics and ability of differentiation into neuron-like cells between rat fetal blood and bone marrow-derived MSCs.
结论:大鼠胎血和骨髓msc的细胞形态、生物学特性无明显差别;两者诱导分化为神经元样细胞的能力无显著差异。
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