Companies that successfully combine online and offline business models may prove to be a big concern for traditional retailers.

成功结合线上和线下商业模式的公司对传统零售商来说可能是一个很大的困扰。

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The other big concern is health care.

另外一项使人关切的问题是医疗保健。

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Safety is a big concern for the private rocket builders, too.

安全也是私营火箭制造商担心的一个大问题。

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The report says food is a big concern for most of the displaced and water too is emerging as a growing problem.

VOA: standard.2009.09.20

Bennett says clean drinking water is the next big concern, especially to prevent an outbreak of diseases such as diarrhea or cholera.

VOA: standard.2010.08.02

Her point of view is growing and so is her income. The IOM's Setiawati says the women are ready to expand their business, but the big concern is how they will market their products without the IOM's assistance.

VOA: standard.2010.04.14

Mr Syme said it was a "big concern" for charities when damaging stories came to light.

BBC: NEWS | UK | Scotland | Charity directors suspended

That issue remains a big concern as tires still shred far too easily despite pre-race modifications.

NPR: Alonso Thrills Home Fans With Spanish GP Win

Which specifically in this country, and for good reason, are a big concern, which is okay.

FORBES: Daimler's Dieter Zetsche: Sales Are Not Our No. 1 Priority