Objective To investigate the distribution pattern and content of collagen fibers of atrium cordis in children with normal and ventricular septal defect.

目的探讨正常和室间隔缺损儿童心房胶原纤维的分布及其含量。

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The collagen fibers in atrium cordis were redistributed and increased in content significantly in some areas in children with ventricular septal defect.

室间隔缺损儿童心房胶原纤维部分区域明显改变，含量显著增加。

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Methods An experimental pulmonary embolism model in rats was made by injecting coagulated thrombus in vitro into right atrium cordis through a conductor.

方法采用改良的导管方法将体外已凝的大鼠血栓注入右心房制备大鼠急性肺栓塞模型。

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