"My doctor says your alk phosphatase number is high," Feiler recalls.

“医生告诉我说，你的碱性磷酸酶指数(alk phosphatase)很高。”费勒回忆道。

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There are other examples of success in specifically targeting genetic changes in never-smokers with lung cancer, such as treatments of tumors with alterations in the EML4-ALK gene.

针对不吸烟者的基因改变进行靶向治疗，这有些其它的成功例子，比如针对有EML4-ALK基因改变的肿瘤进行的治疗。

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In 2007 a group of researchers discovered that the fusion of two normally independent genes, EML4 and ALK, into one aberrant gene seems to drive the formation of tumours.

2007年一个研究小组发现，两种普通基因(EML4和ALK)和一个异常化基因的融合能形成肿瘤。

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Most notably, we completed U.S. and Japanese filings for crizotinib in ALK-positive non-small cell lung cancer and U.S. and EU filings for axitinib in advanced renal cell carcinoma.

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Another carrier favored by Neidl is Alaska Air Group (nyse: ALK - news - people ), the holding company of Alaska Airlines, which serves cities along the west coast of Canada, the U.S. and Mexico.

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Separately, Pfizer said that the Food and Drug Administration has approved Xalkori capsules, which the company calls the first-ever drug targeting anaplastic lymphoma kinase, or ALK, for the treatment of locally advanced or metastatic non-small cell lung cancer that is ALK-positive.

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