Once professional brokers got in on the act, though, the nature of exchanges began to shift. Buyers and sellers lost some of their close contact with markets.

自从专业经纪人介入到交易中，交易的性质即开始发生变化：买主及卖主丧失了与市场的一些联系；交易变得越来越复杂，比如说可以以当前价格买卖将来的货物。

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Instead, these data (albeit based on only ten animals) do suggest that only those animals which are in close contact with people act as reservoirs.

借由这项资料可得知(虽然只有十个北极熊样本)，抗药基因不只存在于跟人类有接触的动物身上。

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To improve the situation, physicians need to calculate the CHADS2 score during every AF patient contact, and then act on the findings.

为了改善这种环境，医生需要对每一个房颤病人接触过程中计算CHADS2评分，然后根据结果做出处理。

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