Rheumatoid Arthritis – Rheumatoid arthritis affects 2.1 million Americans, most of them women, according the Arthritis Foundation. In this autoimmune disorder, the joints become painful, swollen, stiff and, in severe cases, deformed. One medicine in development is a recombinant version of human alpha-fetoprotein (hAFP), an immunomodulatory serum protein that, at high levels, has long been associated with remission of many autoimmune diseases. In clinical trials, the medicine has been well tolerated and supports the idea that hAFP may be an important new therapeutic option in the treatment of rheumatoid arthritis and other autoimmune disorders. The medicine is also being studied in additional autoimmune disorders.
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