METHODS A single oral dose of two preparations was given to 20 healthy male volunteers according to a randomized crossover design.
方法采用随机二交叉设计试验,20例男性健康志愿受试者,单剂量口服受试制剂盐酸金刚乙胺颗粒和参比制剂盐酸金刚乙胺片。
METHODS A single oral dose of 40 mg paroxetine hydrochloride was given to 18 healthy volunteers. The concentrations of paroxetine in plasma were assayed by HPLC-MS method.
方法18名健康男性志愿者,单剂量口服盐酸帕罗西汀片,在设计的时间点取静脉血,血药浓度采用液相色谱质谱(HPLCMS)法测定。
AIM: To compare pharmacokinetics and bioavailability of 2 midazolam tablets in 20 healthy volunteers after a single oral dose (15 mg) of domestic midazolam maleate tablets compared with imported.
目的:比较国产和进口马来酸咪达唑仑片在2 0名男性健康受试者中的药物动力学和相对生物利用度。
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