OBJECTIVE:To elucidate the effect of ondansetron(OND), a 5-HT3 receptor antagonist, on the morphine-induced conditioned place preference(CPP) in mice and its possible mechanism.
目的:探讨5-HT3型受体特异性拮抗剂奥丹西隆对吗啡诱导的条件性位置偏爱(CPP)效应的影响及其可能机制。
The success of Ondansetron in market leads to further research into 5-ht3 receptor antagonist and rapid development of research on the structure-activity relationship of 5-ht3 receptor antagonist.
由于昂丹司琼在市场上的成功导致对5 - HT 3受体拮抗剂大量的研究,同时对5 - HT 3受体拮抗剂的构效关系的研究也进展迅速。
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