目的:研究高浓度葡萄糖是否能抑制兔胸主动脉内皮依赖的血管舒张以及可能的机制。
AIM: To determine whether high concentration of glucose inhibits endothelium-dependent vasorelaxation of rabbit aortic artery and possible mechanisms.
结论高浓度葡萄糖可使视网膜混合培养细胞增殖,其机制可能部分与NO产生量减少有关。
Conclusion High glucose can stimulate the proliferation of retina cells, the mechanism maybe lies in decreasing the concentration of NO.
结论:高浓度葡萄糖抑制内皮依赖的血管舒张,这种作用不是通过增加氧自由基的产生介导的。
CONCLUSION: High concentration of glucose inhibited endothelium-dependent vasorelaxation and this effect was unlikely mediated through activating oxygen-derived free radical production.
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