...子中叔 胺基的N-甲基,代谢物与酶分子中血红蛋白亚铁形成亚 硝基复合物,从而使酶失活; ③非选择性抑制 ( nonselective inhibition):指药物对多个CYP亚族酶都有 抑制作用。 如西米替丁咪唑环上的N与CYP亚铁血红素部分配体 非选择性结合,引起酶活性障碍。
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它们不但抑制均相、非均相结焦过程，而且会影响裂解产物分布和提高乙烯选择性。
The coking inhibitors not only inhibit the homogeneous and heterogeneous coke deposition processes but also influence pyrolysis product distribution and ethylene selectivity as well.
伐地那非是一种新型高选择性磷酸二酯酶5型抑制剂，它对心血管系统的安全性已被多项临床试验所证实。
Vardenafil, as a novel and highly selective phosphodiesterase 5 inhibitor, has been proved by many clinical trials to be quite safe for the cardiovascular system.
伐地那非是一种高选择性的新型磷酸二酯酶5抑制剂，是广泛ED人群的一线治疗药物。
Vardenafil, a novel and highly selective phosphodiesterase 5 inhibitor, is the first line therapy for the broad ED population.
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