5 群体药物动力学研究 Regnier等[26]测定了63只犬在静脉注射马波沙星之后药物在眼水样液中的含量,采用非线性混合效应(NONMEM)模型对检测数据进行统计分析。利用群体药代动力学参数模拟i.v.
基于12个网页-相关网页
非线性混合效应模型 NONMEM ; Nonlinear Mixed Effect Model ; NLME models
非线性混合效应模型法 NONMEM ; Nonlinear Mixed Effect Model ; Nonlinear mixed effects modeling
用非线性混合效应模型 nonlinear mixed effect model
用非线性混合效应模型（NONMEM）考察固定效应对丙戊酸相对清除率的影响。
The influence of the fixed effects on relative clearance of VPA was investigated using Nonlinear Mixed Effect Model(NONMEM) .
目的探讨非线性混合效应模型在交叉试验等级资料中的应用，为临床试验交叉设计资料的正确分析提供方法学参考。
Objective To explore the application of nonlinear mixed models in ordered categorical data of cross-over trial analysis and hence provide methodology reference.
同时考虑样地的随机效应、观测数据的时间序列相关性及不同初植密度的混合模型模拟精度比传统的非线性回归方法模拟精度高。
The precision of mixed model considering plot random effects, time series error autocorrelation and different plantation density at one time is better than that of ordinary regression analysis method.
应用推荐