目的：探讨随意筋膜皮瓣修复小腿难愈创面的治疗效果。
Objective: To investigate the repairing effects of random fasciocutaneous flap for refractory wound in legs.
如何加快伤口愈合一直是创伤领域研究的热点，但难愈创面的治疗一直缺乏有效手段。
Although many studies are focused on how to accelerate wound healing, there are still no efficient methods for hard-healing wound.
本文着重讨论了难愈创面的发生机制，并介绍了各种治疗手段如皮肤替代物、 生长因子、创面负压治疗技术等的应用进展。
This article focuses on the pathogenesis of chronic wound and introduces progress in various kinds of treatment, such as skin substitute, growth factors, negative pressure treatment, etc.
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