设计非随机化临床试验。
介绍多种疾病亚型、各中心分配例数不等的临床试验随机化方案的设计。
A design for randomized protocol of multi-center clinical trial dealing with multi-subtype disease and unequally distributed cases in centers was introduced in this article.
结果：多中心临床试验中央随机系统实现了受试者筛选、随机化、药物发放和药物供应链管理等功能。
Results: The central randomization system could be used to screen subjects, randomize subjects, dispense drugs and administrate the drug supply chain.
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