如肿瘤细胞出现间变，细胞密度增加，多形性，核深染，出现核分裂象等，则为间变性星形细胞瘤(anaplastic astrocytoma)，为恶性肿瘤。
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P53相关的基因组不稳定性在从间变性星形细胞瘤(anaplasticastrocytoma，AA)进展到GM的致命性转化过程中RJ能并非主要的遗传学缺陷．但可能对这一恶性转化过程起着推波助澜的作用。
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级为间变性星形细胞瘤 anaplastic astrocytoma
但间变性星形细胞瘤 anaplastic astrocytoma
包括间变性星形细胞瘤 anaplastic astrocytoma
结论：间变性星形细胞瘤和肥胖细胞性星形细胞瘤更具恶性，易复发。
Conclusion The result suggest that anaplastic astrocytoma and gemistocytic astrocytoma are more malignant and more recurrent.
结果间变性星形细胞瘤7例，多形性胶质母细胞瘤3例，少突胶质瘤1例，低级别胶质瘤1例。
Results There were 7 cases with anaplastic astrocytoma, 3 cases with glioblastoma multiforme, 1 cases with oligodendroglioma, 1 cases with lower grade glioma.
结果：随访期间内44.8%患者肿瘤缩小，间变性星形细胞瘤中位控制时间15个月，胶质母细胞瘤9个月。
Results:There were 44 8% of the tumors shrank. Median tumor local control interval was 10 months(15 months for AA and 9 months for GBM).
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