结论福辛普利不仅能防治心肌肥厚,而且能保护肌浆网钙泵功能,防止心肌钙超载损伤。
Conclusions Fosinopril could not only prevent and treat myocardial hypertrophy, but also could maintain the functions of SERCA and prevent myocardial calcium overload.
钙超载是心肌缺血再灌注不可逆损伤的最后通路,但其具体作用途径有待于进一步研究。
Calcium overload is the final pathway of myocardial ischemia reperfusion injury, but the concrete mechanism needs further research.
结论:健心合剂对大鼠心肌缺血损伤具有保护作用,其机理可能与钙超载有关。
Conclusion: Jianxin mixture has a protective effect on myocardial ischemia injury in the rats, which is due to its inhibition of calcium overload.
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