其它促成催化的因素来自结合水分子，金属离子或其它因子。
Additional contributions to catalysis can come from bound water molecules, metal ions, or other factors.
和人工催化剂相比，酶所包裹的金属离子种类十分有限。
Compared with artificial catalysts, enzymes are wrapped around a relatively limited range of metals at their core.
金属离子可以是辅助因素的催化中心，也可以帮助形成酶活性所必须的构象。
The metal ion may be the catalytic center of the cofactor, or it may serve to bind the enzyme and substrate together to hold the enzyme in a catalytically active conformation.
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