所谓细胞重编程技术,就是通过在体细胞内同时表达几种外源性重编程因子(reprogramming factor)的方法让体细胞重新获得多向分化的能力,并重新成为干细胞的一项技术。这项技术的出现让科学家们能够非常容易地构建出各种人体.
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通过一种病毒把这些重编程因子的混合物引入细胞中,这些细胞发生了变化并在实验室中发育成了胚胎样干细胞群。
After the cocktail of reprogramming factors had been introduced into the cells via a virus, the cells changed and developed in the laboratory into colonies of embryonic-like stem cells.
本文主要从转录因子、表观遗传和信号转导等角度,介绍了细胞重编程分子机制研究方面的进展和未来的方向。
In the present paper we review the role and molecular mechanism of transcription factors, epigenetic regulation and cell signaling in cell reprogramming.
强制表达几个转录因子可以使体细胞重编程为诱导的多潜能干细胞(iPS cells)。
Somatic cells can be reprogrammed into induced pluripotent stem (iPS) cells by enforced expression of transcription factors.
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