重大伤亡事故，是《刑法》及其司法解释中的概念，主要用于对安全生产领域犯罪的定罪量刑。根据《刑法》第一百三十四条、第一百三十五条，“在生产、作业中违反有关安全管理的规定”或“安全生产设施或者安全生产条件不符合国家规定”，并因此发生重大伤亡事故的，有关责任人员将会被追究刑事责任。
近年来在工程施工中因坍塌事故而造成的重大伤亡事故屡有发生。
In recent years, serious accidents caused by collapse have repeatedly happened in engineering construction.
第四十六条矿山企业主管人员违章指挥、强令工人冒险作业，因而发生重大伤亡事故的，依照刑法有关规定追究刑事责任。
Article 38 Mining enterprises shall, in accordance with regulations of the State, give pensions or compensations for workers and staff members who died or were injured in accidents at mines.
现在有一些地方对安全生产没有给予应有的重视，有些企业为了降低成本，安全设施不到位，造成了重大伤亡事故的频繁发生。
At present, some places do not pay due attention to safe production, some enterprises in order to decrease production cost don't set up safe facilities which often result heavy casualties.
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