虽然许多因素会影响药物的治疗过程,但遗传因素肯定在其中发挥了重要作用[3].遗传药理学(pharmacogenetics)是研究个体基因的变异对药物代谢、功效和不良反应的不同影响的学科,其最终目的是在患者用药之前可以根据个体的基因型预测药物的疗...
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Metabolism, disposition and effect of drug and carcinogen are mediated by xenobiotic response related genes. Discovery and correlation or association study for SNPs in these genes are important parts of individualized treatment-oriented pharmacogenetics and population prevention-oriented genetic epidemiology of cancer.
外源化合物反应系统介导了药物毒物等的代谢、处置和效应，对这些基因群SNP的发掘和关联或相关性研究，是着眼于个体化治疗的遗传药理学和着眼于人群预防的肿瘤遗传流行病学的重要内容。
参考来源 - 中国人外源化合物反应相关基因的单核苷酸多态性研究·2,447,543篇论文数据，部分数据来源于NoteExpress
与人类相似的雄性和雌性小鼠不仅性别是不同的，它们各自的遗传反应往往会得到与人们期待相反的药理学结果。
Like their human counterparts, male and female mice are not only different, their respective genetic responses can often be the reverse of what you'd expect from pharmacological results.
反义核酸药物是基因药理学的一个新领域，对于肿瘤、遗传病以及传染病的防治具有重要意义。
As a new territory of genetic pharmacology, antisense nucleic acid drug has been promoting the development of tumor research as well as the study of genetic and infectious diseases.
基础医学研究的前沿学科是：生物信息学及其带动的医学分子生物学、遗传学、免疫学、内分泌学、药理学和神经科学等。
The frontier in the basic medicine are: bioinformatics and it will induce the medical molecular biology, genetics, immunology, endocrinology, pharmacology, neurology, etc.
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