...造血前体细胞 体外扩增 [gap=1114]Key Words］proliferating cell nuclear antigen antisense oligodeoxynucleotide; hematopoietic precursor cell; expansion in vitro ..
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目的： 用间质干细胞（MSC）体外模拟造血微环境，探讨脐带血造血前体细胞在MSC微环境中的增殖和分化特性。
AIM: To investigate the proliferation and differentiation patterns of hematopoietic precursors from cord blood in mesenchymal stem cell(MSC) microenvironment.
结论：人脐血CD34+ 细胞群中存在造血基质细胞的前体细胞，人脐血贴壁细胞具有造血基质细胞的某些生物学特点。
It is concluded there are hematopoitic adherent precursors in cord blood CD34+ cells and the HUCBAC shows some biological behavior of hematopoitic stromal cells.
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