1988年,Huston等[7]在VH和VL链之间通过一个连接肽(linker peptide)来增强其稳定性,称为单链抗体(ScFv),但ScFv在很多情况下,稳定性也不理想,容易解离形成多聚物沉淀,而dsFv抗体是靠链间二硫键...
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胰岛素前体经剪切后形成的胰岛素和连接肽 (connecting peptide), C 肽同时被释放入血。 即 由于血中 C 肽与胰岛素的分泌量呈平行关系, 因此测定 C 肽含量可反映 B 细胞的分泌功能。
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In this work, we utilize cholera toxin B-subunit(CTB) as a transmucosal carrier. Ctb and Lembrokinase(LK) gene, separated by a linker peptide, was expressed in soybean cells.
本研究利用霍乱毒素B-亚基(cholera toxin B-subunit, CTB)作为肠道黏膜转运载体,辅助药物蛋白穿过肠上皮细胞的运输,我们将CTB基因和蚓激酶(Lembrokinase, LK)的基因通过一段柔性连接肽相连,并使其在大豆细胞内表达。
参考来源 - 大豆生物反应器表达融合蛋白CTB·2,447,543篇论文数据,部分数据来源于NoteExpress
同时,肿瘤细胞表面常见的酶切断TRAIL和石墨烯之间的连接肽。
Meanwhile, enzymes that are common on the surface of cancer cells sever the peptides linking the TRAIL and the graphene.
这就是蛔虫的行为为何无法通过接线图计算得出:在蛔虫250个神经肽的影响下,连接的形式时刻在变化着?
That may be a reason why the worm's behavior cannot be computed from the wiring diagram: the pattern of connections is changing all the time under the influence of the worm's 250 neuropeptides.
血管紧张素-(1 - 7)是一种能连接到细胞膜表面蛋白的小肽,仅当细胞活跃的生长时,这种小肽与表面蛋白结合后即能阻止细胞的生长。
Angiotensin - (1-7) is a small peptide that binds to proteins on the surface of cells and prevents cell growth - but only if the cell is actively growing when the binding occurs.
They also have binding sites for antigen, but they are sort of two IgG type molecules bound together by another peptide chain.
同样IgA抗体表面也有与抗原结合位点,但它们就像两个IgG型分子,通过肽链相互连接
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