这是我最大的问题。

That was my biggest problem.

youdao

我听到的两个最大的报怨，一是称Android手机的升级更新不够快(这是真的！)，二是许多Android设备的系统功能不完整——这恰恰是第一个问题的症状。

The two biggest complaints I hear are that Android devices don't get updated quickly enough (True!) and that Android devices are fragmented — which is a symptom of the first problem.

youdao

答：亲爱的，这是我此生最大的遗憾，也是我必须作出回答、以及为守护者们负起责任的问题。

That, beloved, is my biggest regret of this life, and something that I will have to answer and be accountable to the Guardians for.

youdao

I had an injury as well, so I couldn't stand. That was my big problem.

我受过伤，所以我不能站着。这是我最大的问题。

记忆犹新的作品 - SpeakingMax英语口语达人