...事件的基因大致可以分为以下几类，即转移起始基因（metastasis initiation gene）、转移进展基因（metastasis progression gene）和转移毒力基因（..
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PTEN基因LOH是乳腺癌发生晚期阶段的重要改变之一，它在乳腺癌的进展和转移过程中可能发挥重要作用。
LOH of PTEN gene may be a relatively late event in breast cancer development, which may play important roles on invasion and metastasis in breast cancer.
目的综述乳腺癌转移抑制基因1（BRMS1）在抑制乳腺癌转移中的作用机理研究进展。
Objective To review the recent studies on the suppressing function of breast cancer metastasis suppressor 1 (BRMS1) in breast cancer metastasis.
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用，但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
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