转基因是近年来在生命科学领域广泛应用的新兴技术,目前80%以上的转基因动物模型是利用显微注射法构建完成的。
Gene transfer is a new and widely used technology in bioscience field. At present over 80 percent of transgenic animal models are constructed by means of microinjection.
近年来,随着转基因动物制备技术的日趋成熟与完善,建立转基因动物模型已经成为研究真核基因表达调控的一种重要手段。
Recently, with the development of transgenic technology, producing transgenic animal model has become an important way to study the expression regulation of eukaryotic genes.
目的建立系统表达肝素结合性表皮生长因子的转基因动物模型,利用转基因动物模型研究HB - EGF与组织纤维化的关系。
Objective to construct heparin-binding epidermal growth factor-like growth factor transgenic mice in order to investigate the role of HB-EGF in the fibrosis of tissues.
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