体外实验中对相应受体进行刺激后导致对细胞外信号调节酶（ERK）的激活有促进作用。
Stimulation of this receptor in vitro results in up-regulation of activated extracellular signal–regulated kinase (ERK).
AMPK被激活后在增加骨骼肌对葡萄糖摄取、增强胰岛素敏感性、增加脂肪酸氧化以及调节基因转录等方面发挥重要作用。
Activated-AMPK plays important roles in increasing glucose uptake in skeletal muscle cells, increasing fatty acid oxidation, improving insulin sensitivity and regulating gene transcription.
我们也对不同水平下调节自噬的分子机制(从转录激活作用到翻译后蛋白修饰作用)方面的最新进展做了文献复习。
We also review the recent advances on the molecular mechanisms that regulate the autophagy machinery at various levels, from transcriptional activation to post-translational protein modification.
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