例如,糖皮质激素受体基因在大脑特定区域的持续表达提高了调节应激反应的能力。
For example, increased expression of the glucocorticoid receptor gene in particular brain regions improves the ability to regulate a stress response.
核受体家族的经典作用机制是在其配基存在下结合在靶基因的应答元件上,从而在转录水平上调节基因的表达。
The classical mechanism for nuclear receptors to regulate gene expression is to bind the hormone response element(HRE) on the target gene in the presence of their ligands.
HR蛋白是细胞核受体辅阻遏物的发现证明HR蛋白是通过在毛发周期中调节基因表达来发挥作用的。
The discovery that the HR protein is a nuclear receptor corepressor indicated that HR function in hair cycling is by regulating gene expression.
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