TOLL样受体4与心肌缺血再灌注损伤 - docin.com豆丁网 （mitogen activated protein kinase，MAPK）家 族中的NF-kB 诱导激酶（NF-kB inducing kinase，NIK），NIK 激活后会进一步活化IkB 家族的α、β 激酶，导致IkB 两个丝 氨酸位点磷酸化，最终导致
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盐诱导激酶 SIK ; salt-inducible kinase
血清诱导激酶 serum-inducible kinase ; SNK
可被血清诱导激酶 serum-inducible kinase ; SNK
可诱导血清诱导激酶 serum-inducible kinase ; SNK
糖皮质激素诱导激酶 SGK
水杨酸诱导的蛋白激酶 SIPK
激酶诱导区域 kinase induced domain ; kinase inducible domain ; KID
糖皮质诱导蛋白激酶 SGPK
诱导蛋白激酶 serum and glucocorticoid inducible protein kinase ; SGK
在小鼠模型中，GNA11突变诱导了自发转移性肿瘤，激活了丝裂原活化蛋白激酶途径。
Mutations in GNA11 induced spontaneously metastasizing tumors in a mouse model and activated the mitogen-activated protein kinase pathway.
因此，本研究的目的是调查金雀异黄素，一种蛋白质酪氨酸激酶抑制剂，对有急性或慢性糖尿病炎症小鼠（诱导脲佐菌素）的影响。
Therefore, the aim of this study is to investigate the effects of genistein, a protein tyrosine kinase inhibitor, on acute and chronic inflammation in diabetic mice (induced by streptozotocin).
低氧条件会直接诱导丙酮酸脱氢酶激酶1 (PDHK1)的表达，它的表达会抑制pdh的活性和TCA循环，从而抑制了随后的代谢通路(4)。
Hypoxia can directly induce pyruvate dehydrogenase kinase 1 (PDHK1) expression, which results in inactivation of PDH and the TCA cycle and subsequent suppression of metabolism (4).
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