肥大细胞除具有识别、吞噬并杀灭病原微生物的功能外,尚能加工、递呈抗原和调节免疫反应。
Mast cells not only have the ability to recognize and phagocytize pathogens, then kill them, but they can also present antigens and regulate immunity response.
淋巴细胞识别由主要组织相容性复合物(MHC)I或II类分子递呈的抗原肽片段。
T lymphocytes recognize antigenic peptide fragments presented by major histocompatibility complex(MHC) class I or class II molecules.
因此,树突状细胞(DC细胞)递呈肿瘤抗原给共培养的CIK细胞,希望可以增强CIK细胞识别肿瘤的能力以及提高其肿瘤杀伤活性。
Hence, dendritic cells (DC) were cultured and engineered to present tumor antigens to CIK cells hoping that this might enhance the recognition of tumor cells and its subsequent killing.
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